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A. Vidybida, "Harnessing thermal fluctuations for selectivity gain," 2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), 2022, pp. 1-3, doi: 10.1109/ISOEN54820.2022.9789678.
Selectivity of olfactory receptor neuron (ORN) is compared with that of its receptor proteins (R) with fluctuations of odor binding-releasing process taken into account. The binding-releasing process is modeled as N Bernoulli trials, where N is the total number of R per ORN. Dimensionless selectivities for both R and ORN are introduced and compared with each other. It is found the ORN's selectivity can be much higher then that of its receptor proteins. This effect is concentration-dependent. Possible application for biosensors is discussed.
Keywords: sensor, fluctuations, noise, selectivity, electronic